More than 50% of patients with rheumatoid arthritis (RA) have cachexia syndrome characterized by a decrease in skeletal muscle mass and an increase in fat mass due to cytokine-induced changes in energy and protein mechanisms. It is associated with more serious complications such as increased risk of infection, cardiac complications, and premature death as well as symptoms that affect daily life functions such as atrophy, weakness, fatigue and dysfunction in the rheumatoid cachexia muscles, where involvement in skeletal muscles is prominent. More than 5% loss of morbidity in skeletal muscle mass, and more than 40 loss affect mortality significantly. Measures to reduce body mass loss in rheumatoid arthritis include exercise programs to boost and endurance, adequate consumption of proteins, and anabolic hormone and anticancer therapy. Increased resistance strengthening exercises and endurance exercises have been shown to increase muscle mass in the body without affecting disease activity in RA patients. However, it is difficult for patients to participate in these programs due to reasons such as deformities and disease activation. Therefore, in RA patients, different methods are needed to increase muscle mass without causing disease activation. Muscle hypertrophy is achieved when the neuromuscular electrical stimulation is applied in a stable muscle, that is, strength is increased. Russian current is formed by modulating the continuous sinusoidal wave current with a carrier frequency of 2500 pulses at the time. This continuous sinusoidal wave current is burst modulation with a fixed period of 10 ms followed by a fixed period of 10 ms. The Russian current co-depolarizes the peripheral sensory and motor nerve fibers to provide synchronized motor nerve depolarization and, preferably, increase the activation of fast-twitch type 2 muscle fibers and provide a visible increase in strength.
Dr. Ceyhun NURİ
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